Product Data Sheet
NS3861 fumarate
Catalog No. A67633
NS3861 fumarate is a potent agonist of the heteromeric α3β4 nicotinic acetylcholine receptor (nAChR), exhibiting high affinity with a binding Ki of 0.62 nM. This compound selectively engages with α3β4 nAChRs while also demonstrating varying affinities for other nAChR subtypes, including α3β2 (25 nM), α4β4 (7.8 nM), and α4β2 (55 nM). NS3861 fumarate is primarily used in neurological research to investigate nAChR functions and their roles in neuropharmacology.
Chemical Information
| Catalog Num | A67633 |
|---|---|
| M. Wt | 400.29 |
| Formula | C16H18BrNO4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 216853-60-0 |
| Synonyms | |
| SMILES | BrC1=C(C2=CC(CC3)N(C)C3C2)SC=C1.OC(/C=C/C(O)=O)=O |
Biological Activity
| Description | NS3861 fumarate is a potent agonist of the heteromeric α3β4 nicotinic acetylcholine receptor (nAChR), exhibiting high affinity with a binding Ki of 0.62 nM. This compound selectively engages with α3β4 nAChRs while also demonstrating varying affinities for other nAChR subtypes, including α3β2 (25 nM), α4β4 (7.8 nM), and α4β2 (55 nM). NS3861 fumarate is primarily used in neurological research to investigate nAChR functions and their roles in neuropharmacology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
