Product Data Sheet
SEN12333
Catalog No. A67634
SEN12333 is a potent and selective agonist of the α7 nicotinic acetylcholine receptor (nAChR). It demonstrates high affinity for rat α7 nAChRs, with a Ki value of 260 nM, and functions as a full agonist in calcium flux studies, achieving an EC50 of 1.6 μM. This compound is utilized in research focusing on Alzheimer's disease and schizophrenia, facilitating the exploration of therapeutic interventions targeting cholinergic signaling pathways.
Chemical Information
| Catalog Num | A67634 |
|---|---|
| M. Wt | 339.43 |
| Formula | C20H25N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 874450-44-9 |
| Synonyms | WAY-317538 |
| SMILES | O=C(CCCCN1CCOCC1)NC2=CC=C(C3=CN=CC=C3)C=C2 |
Biological Activity
| Description | SEN12333 is a potent and selective agonist of the α7 nicotinic acetylcholine receptor (nAChR). It demonstrates high affinity for rat α7 nAChRs, with a Ki value of 260 nM, and functions as a full agonist in calcium flux studies, achieving an EC50 of 1.6 μM. This compound is utilized in research focusing on Alzheimer's disease and schizophrenia, facilitating the exploration of therapeutic interventions targeting cholinergic signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
