Product Data Sheet
Br-PBTC
Catalog No. A67635
Br-PBTC is a selective positive allosteric modulator of nicotinic acetylcholine receptors (nAChRs), specifically targeting the α2β2, α2β4, α4β2, α4β4, (α4β2)2α4, and (α4β2)2β2 subtypes with effective concentration (EC50) values ranging from 0.1 to 0.6 μM. By acting on the c-terminal region of the α subunit, Br-PBTC enhances receptor activity, making it a valuable tool for studying nAChR-mediated signaling pathways and their implications in neuropharmacology and related fields.
Chemical Information
| Catalog Num | A67635 |
|---|---|
| M. Wt | 339.25 |
| Formula | C14H15BrN2OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1839519-57-1 |
| Synonyms | |
| SMILES | O=C(C1=CC2=CC=CC(Br)=C2S1)N[C@H]3CNCCC3 |
Biological Activity
| Description | Br-PBTC is a selective positive allosteric modulator of nicotinic acetylcholine receptors (nAChRs), specifically targeting the α2β2, α2β4, α4β2, α4β4, (α4β2)2α4, and (α4β2)2β2 subtypes with effective concentration (EC50) values ranging from 0.1 to 0.6 μM. By acting on the c-terminal region of the α subunit, Br-PBTC enhances receptor activity, making it a valuable tool for studying nAChR-mediated signaling pathways and their implications in neuropharmacology and related fields. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
