Product Data Sheet
Epiboxidine hydrochloride
Catalog No. A67638
Epiboxidine hydrochloride is a potent and selective agonist of the nicotinic acetylcholine receptors (nAChRs), exhibiting Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. This compound, a methylisoxazole analog of the alkaloid Epibatidine, plays a critical role in studying nAChR-mediated signaling pathways. Its high affinity and selectivity make it valuable for research applications in neurobiology and pharmacology, particularly in the exploration of neurological disorders and drug development targeting nAChRs.
Chemical Information
| Catalog Num | A67638 |
|---|---|
| M. Wt | 214.69 |
| Formula | C10H15ClN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 862909-67-9 |
| Synonyms | |
| SMILES | CC1=NOC([C@@H]2[C@@H]3N[C@@H](CC3)C2)=C1.[H]Cl |
Biological Activity
| Description | Epiboxidine hydrochloride is a potent and selective agonist of the nicotinic acetylcholine receptors (nAChRs), exhibiting Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. This compound, a methylisoxazole analog of the alkaloid Epibatidine, plays a critical role in studying nAChR-mediated signaling pathways. Its high affinity and selectivity make it valuable for research applications in neurobiology and pharmacology, particularly in the exploration of neurological disorders and drug development targeting nAChRs. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
