Product Data Sheet

PHA-543613 hydrochloride

Catalog No. A67655

main product photo
PHA-543613 hydrochloride is a potent agonist of the α7 nicotinic acetylcholine receptor (nAChR) with demonstrated brain permeability. This compound selectively targets α3β4, α1β1γδ, α4β2, and 5-HT3 receptors. PHA-543613 hydrochloride has shown significant effects on sensory gating and memory in in vivo models of schizophrenia, making it valuable for research in neuropharmacology and psychopharmacology.
Chemical Information
Catalog NumA67655
M. Wt307.78
FormulaC15H18ClN3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1586767-92-1
Synonyms
SMILESO=C(C1=CC2=C(OC=C2)C=N1)N[C@H]3CN4CCC3CC4.[H]Cl
Biological Activity
DescriptionPHA-543613 hydrochloride is a potent agonist of the α7 nicotinic acetylcholine receptor (nAChR) with demonstrated brain permeability. This compound selectively targets α3β4, α1β1γδ, α4β2, and 5-HT3 receptors. PHA-543613 hydrochloride has shown significant effects on sensory gating and memory in in vivo models of schizophrenia, making it valuable for research in neuropharmacology and psychopharmacology.
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