Product Data Sheet
Lobelanidine
Catalog No. A67670
Lobelanidine is a selective antagonist of nicotinic acetylcholine receptors (nAChR), effectively inhibiting the α7 nAChR response as well as the α3β2/α3β4 nAChR responses, with IC50 values of 2.8 μM and 8.2 μM, respectively. This compound serves as a valuable tool for investigating the role of nAChRs in neuronal signaling and various neurological disorders. Its pharmacological properties make it suitable for research applications in neurobiology, drug discovery, and toxicology studies.
Chemical Information
| Catalog Num | A67670 |
|---|---|
| M. Wt | 339.47 |
| Formula | C22H29NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 552-72-7 |
| Synonyms | |
| SMILES | OC(CC1N(C(CCC1)CC(O)C2=CC=CC=C2)C)C3=CC=CC=C3 |
Biological Activity
| Description | Lobelanidine is a selective antagonist of nicotinic acetylcholine receptors (nAChR), effectively inhibiting the α7 nAChR response as well as the α3β2/α3β4 nAChR responses, with IC50 values of 2.8 μM and 8.2 μM, respectively. This compound serves as a valuable tool for investigating the role of nAChRs in neuronal signaling and various neurological disorders. Its pharmacological properties make it suitable for research applications in neurobiology, drug discovery, and toxicology studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
