Product Data Sheet

nAChR antagonist 1

Catalog No. A67673

main product photo
nAChR antagonist 1 is a selective antagonist of the α7 nicotinic acetylcholine receptor, exhibiting an IC50 value of 3.3 μM. This compound is valuable for studying the role of α7 nAChR in various neurological conditions, including schizophrenia, Alzheimer's disease, and inflammatory disorders. Its modulatory effects on neurotransmission make it a relevant tool for exploring therapeutic strategies in these disease contexts.
Chemical Information
Catalog NumA67673
M. Wt338.40
FormulaC19H22N4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2987393-37-1
Synonyms
SMILESCOC1=CC(C2=CC=C(C=C2)C3=NOC4(N3)CCN(CC4)C)=CC=N1
Biological Activity
DescriptionnAChR antagonist 1 is a selective antagonist of the α7 nicotinic acetylcholine receptor, exhibiting an IC50 value of 3.3 μM. This compound is valuable for studying the role of α7 nAChR in various neurological conditions, including schizophrenia, Alzheimer's disease, and inflammatory disorders. Its modulatory effects on neurotransmission make it a relevant tool for exploring therapeutic strategies in these disease contexts.
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