Anabasine hydrochloride
Catalog No. A67694

Anabasine hydrochloride is a potent agonist of nicotinic acetylcholine receptors (nAChRs). This alkaloid, derived from tobacco (Nicotiana), functions as a full agonist, inducing depolarization in TE671 cells that endogenously express human fetal muscle-type nAChRs (EC50 = 0.7 µM). Anabasine hydrochloride is relevant for research applications in neurobiology and toxicology, particularly in studies exploring nAChR signaling and muscle contraction mechanisms.
Chemical Information
| Catalog Num | A67694 |
|---|---|
| M. Wt | 198.69 |
| Formula | C10H15ClN2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 53912-89-3 |
| Synonyms | (S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride |
| SMILES | [H]Cl.C1([C@H]2NCCCC2)=CC=CN=C1 |
Biological Activity
| Description | Anabasine hydrochloride is a potent agonist of nicotinic acetylcholine receptors (nAChRs). This alkaloid, derived from tobacco (Nicotiana), functions as a full agonist, inducing depolarization in TE671 cells that endogenously express human fetal muscle-type nAChRs (EC50 = 0.7 µM). Anabasine hydrochloride is relevant for research applications in neurobiology and toxicology, particularly in studies exploring nAChR signaling and muscle contraction mechanisms. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


