Product Data Sheet

nAChR antagonist 3

Catalog No. A67707

main product photo
nAChR antagonist 3 is a selective antagonist of the α7 nicotinic acetylcholine receptor, demonstrating an IC50 of 0.86 μM. It exhibits protective effects against toxicity induced by paraoxon, making it a valuable tool for studying organophosphate poisoning. This compound is suitable for research applications focusing on neuroprotection and receptor modulation associated with cholinergic signaling pathways.
Chemical Information
Catalog NumA67707
M. Wt431.17
FormulaC16H21Br2N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3114746-65-2
Synonyms
SMILESCC(C)(N1CCC2(CC1)NC(C3=CC(Br)=CC(Br)=C3)=NO2)C
Biological Activity
DescriptionnAChR antagonist 3 is a selective antagonist of the α7 nicotinic acetylcholine receptor, demonstrating an IC50 of 0.86 μM. It exhibits protective effects against toxicity induced by paraoxon, making it a valuable tool for studying organophosphate poisoning. This compound is suitable for research applications focusing on neuroprotection and receptor modulation associated with cholinergic signaling pathways.
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