Product Data Sheet
Nelonicline citrate
Catalog No. A67724
Nelonicline citrate is a selective agonist of the α7 nicotinic acetylcholine receptor (nAChR) with high affinity, as demonstrated by a Ki value of 12.3 nM in human brain tissue. This compound is primarily utilized in research investigating schizophrenia and Alzheimer's disease, providing insights into the modulation of cognitive processes and synaptic plasticity associated with these neurological disorders. Its oral bioavailability makes it a valuable tool for in vivo studies.
Chemical Information
| Catalog Num | A67724 |
|---|---|
| M. Wt | 505.54 |
| Formula | C23H27N3O8S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1026136-84-4 |
| Synonyms | ABT-126 citrate |
| SMILES | O=C(O)CC(O)(CC(O)=O)C(O)=O.[C@@H]1([C@H]2C[C@H](C3)C[C@@H]1C[N@]3C2)OC4=NN=C(C5=CC=CC=C5)S4 |
Biological Activity
| Description | Nelonicline citrate is a selective agonist of the α7 nicotinic acetylcholine receptor (nAChR) with high affinity, as demonstrated by a Ki value of 12.3 nM in human brain tissue. This compound is primarily utilized in research investigating schizophrenia and Alzheimer's disease, providing insights into the modulation of cognitive processes and synaptic plasticity associated with these neurological disorders. Its oral bioavailability makes it a valuable tool for in vivo studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
