Product Data Sheet

Estradiol 3-sulfate 17-glucuronide potassium

Catalog No. A67800

main product photo
Estradiol 3-sulfate 17-glucuronide potassium is an endogenous metabolite derived from estradiol, specifically targeting the multidrug resistance protein (MRP). It is known to inhibit MRP-mediated transport of 17β-Estradiol 17-(β-D-Glucuronide) with an inhibition constant (Ki) of 22 μM. This compound is useful in studying the pharmacokinetics of estrogenic compounds and understanding their role in hormone metabolism and transport mechanisms.
Chemical Information
Catalog NumA67800
M. Wt604.75
FormulaC24H30K2O11S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.10392-35-5
Synonyms
SMILESC[C@@]12[C@](CC[C@@H]2O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O[K])=O)([H])[C@@]4([H])[C@@](CC1)([H])C5=CC=C(OS(=O)(O[K])=O)C=C5CC4
Biological Activity
DescriptionEstradiol 3-sulfate 17-glucuronide potassium is an endogenous metabolite derived from estradiol, specifically targeting the multidrug resistance protein (MRP). It is known to inhibit MRP-mediated transport of 17β-Estradiol 17-(β-D-Glucuronide) with an inhibition constant (Ki) of 22 μM. This compound is useful in studying the pharmacokinetics of estrogenic compounds and understanding their role in hormone metabolism and transport mechanisms.
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