Estradiol 3-sulfate 17-glucuronide potassium
Catalog No. A67800

Estradiol 3-sulfate 17-glucuronide potassium is an endogenous metabolite derived from estradiol, specifically targeting the multidrug resistance protein (MRP). It is known to inhibit MRP-mediated transport of 17β-Estradiol 17-(β-D-Glucuronide) with an inhibition constant (Ki) of 22 μM. This compound is useful in studying the pharmacokinetics of estrogenic compounds and understanding their role in hormone metabolism and transport mechanisms.
Chemical Information
| Catalog Num | A67800 |
|---|---|
| M. Wt | 604.75 |
| Formula | C24H30K2O11S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 10392-35-5 |
| Synonyms | |
| SMILES | C[C@@]12[C@](CC[C@@H]2O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O[K])=O)([H])[C@@]4([H])[C@@](CC1)([H])C5=CC=C(OS(=O)(O[K])=O)C=C5CC4 |
Biological Activity
| Description | Estradiol 3-sulfate 17-glucuronide potassium is an endogenous metabolite derived from estradiol, specifically targeting the multidrug resistance protein (MRP). It is known to inhibit MRP-mediated transport of 17β-Estradiol 17-(β-D-Glucuronide) with an inhibition constant (Ki) of 22 μM. This compound is useful in studying the pharmacokinetics of estrogenic compounds and understanding their role in hormone metabolism and transport mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


