Product Data Sheet

N,N-Dimethyl-idarubicin

Catalog No. A67824

main product photo
N,N-Dimethyl-idarubicin is a powerful histone evictor derived from idarubicin, functioning through a unique mechanism that avoids the induction of DNA double-strand breaks. This anthracycline compound exhibits effective cytotoxicity against Doxorubicin-resistant cells that overexpress the ABCB1 transporter. Its distinct action makes it valuable for research in cancer biology and therapeutic resistance studies.
Chemical Information
Catalog NumA67824
M. Wt525.55
FormulaC28H31NO9
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3033865-16-3
Synonyms
SMILESOC1=C2C(C(C3=CC=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N(C)C)=C1C[C@](O)(C4)C(C)=O
Biological Activity
DescriptionN,N-Dimethyl-idarubicin is a powerful histone evictor derived from idarubicin, functioning through a unique mechanism that avoids the induction of DNA double-strand breaks. This anthracycline compound exhibits effective cytotoxicity against Doxorubicin-resistant cells that overexpress the ABCB1 transporter. Its distinct action makes it valuable for research in cancer biology and therapeutic resistance studies.
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SHIPPING AND STORAGE
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