Product Data Sheet
Coccinine
Catalog No. A67833
Coccinine is an alkaloid with a primary mechanism as a weak inhibitor of the serotonin transporter (SERT) and P-glycoprotein (P-gp), exhibiting IC50 values of 196.3 μM and 0.96 mM, respectively. This compound displays notable anti-tumor activity across various cancer cell lines, including MCF7, Hs578T, MDA-MB-231 (breast cancer), HCT-15 (colon cancer), and A549 (lung cancer). Coccinine serves as a valuable tool in the research of tumor biology and neurological disorders.
Chemical Information
| Catalog Num | A67833 |
|---|---|
| M. Wt | 301.34 |
| Formula | C17H19NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 485-57-4 |
| Synonyms | (-)-Coccinine |
| SMILES | CO[C@@H]1C=C2[C@]3([H])C4=CC(OCO5)=C5C=C4C[N@]([C@@]2([H])C[C@@H]1O)C3 |
Biological Activity
| Description | Coccinine is an alkaloid with a primary mechanism as a weak inhibitor of the serotonin transporter (SERT) and P-glycoprotein (P-gp), exhibiting IC50 values of 196.3 μM and 0.96 mM, respectively. This compound displays notable anti-tumor activity across various cancer cell lines, including MCF7, Hs578T, MDA-MB-231 (breast cancer), HCT-15 (colon cancer), and A549 (lung cancer). Coccinine serves as a valuable tool in the research of tumor biology and neurological disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
