5-BDBD
Catalog No. A67882

5-BDBD is a selective antagonist of the P2X4 receptor, demonstrating potent inhibition of rP2X4R-mediated currents with an IC50 of 0.75 μM. This compound effectively interferes with both basal and acute hyperalgesia induced by nitroglycerin (NTG). 5-BDBD is valuable for studying pain mechanisms and the role of purinergic signaling in nociception.
Chemical Information
| Catalog Num | A67882 |
|---|---|
| M. Wt | 355.19 |
| Formula | C17H11BrN2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 768404-03-1 |
| Synonyms | |
| SMILES | O=C1CN=C(C2=CC=CC(Br)=C2)C(OC3=CC=CC=C34)=C4N1 |
Biological Activity
| Description | 5-BDBD is a selective antagonist of the P2X4 receptor, demonstrating potent inhibition of rP2X4R-mediated currents with an IC50 of 0.75 μM. This compound effectively interferes with both basal and acute hyperalgesia induced by nitroglycerin (NTG). 5-BDBD is valuable for studying pain mechanisms and the role of purinergic signaling in nociception. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


