Product Data Sheet

5-BDBD

Catalog No. A67882

main product photo
5-BDBD is a selective antagonist of the P2X4 receptor, demonstrating potent inhibition of rP2X4R-mediated currents with an IC50 of 0.75 μM. This compound effectively interferes with both basal and acute hyperalgesia induced by nitroglycerin (NTG). 5-BDBD is valuable for studying pain mechanisms and the role of purinergic signaling in nociception.
Chemical Information
Catalog NumA67882
M. Wt355.19
FormulaC17H11BrN2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.768404-03-1
Synonyms
SMILESO=C1CN=C(C2=CC=CC(Br)=C2)C(OC3=CC=CC=C34)=C4N1
Biological Activity
Description5-BDBD is a selective antagonist of the P2X4 receptor, demonstrating potent inhibition of rP2X4R-mediated currents with an IC50 of 0.75 μM. This compound effectively interferes with both basal and acute hyperalgesia induced by nitroglycerin (NTG). 5-BDBD is valuable for studying pain mechanisms and the role of purinergic signaling in nociception.
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