Product Data Sheet
NF023 hexasodium
Catalog No. A67889
NF023 hexasodium is a selective and competitive antagonist of the P2X1 receptor, demonstrating an IC50 value of 0.21 μM. While showing significantly higher IC50 values of 28.9 μM, > 50 μM, and > 100 μM for human P2X3, P2X2, and P2X4 receptor-mediated responses respectively, it provides a robust tool for investigating P2X1 receptor functions. This reagent is valuable in pharmacological research and studies exploring the role of purinergic signaling in various physiological and pathological processes.
Chemical Information
| Catalog Num | A67889 |
|---|---|
| M. Wt | 1162.88 |
| Formula | C35H20N4Na6O21S6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 104869-31-0 |
| Synonyms | |
| SMILES | O=C(C1=CC(NC(NC2=CC(C(NC(C(C([S](=O)(O[Na])=O)=C3)=C4C=C3[S](=O)(O[Na])=O)=CC=C4[S](=O)(O[Na])=O)=O)=CC=C2)=O)=CC=C1)NC(C(C([S](=O)(O[Na])=O)=C5)=C6C=C5[S](=O)(O[Na])=O)=CC=C6[S](=O)(O[Na])=O |
Biological Activity
| Description | NF023 hexasodium is a selective and competitive antagonist of the P2X1 receptor, demonstrating an IC50 value of 0.21 μM. While showing significantly higher IC50 values of 28.9 μM, > 50 μM, and > 100 μM for human P2X3, P2X2, and P2X4 receptor-mediated responses respectively, it provides a robust tool for investigating P2X1 receptor functions. This reagent is valuable in pharmacological research and studies exploring the role of purinergic signaling in various physiological and pathological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
