Product Data Sheet
Sivopixant
Catalog No. A67894
Sivopixant is a selective antagonist of the P2X3 receptor, exhibiting a potent inhibitory activity with an IC50 of 4.2 nM for P2X3 and 1100 nM for P2X2/3. This compound demonstrates significant analgesic properties, making it valuable for research focused on pain pathways and therapeutic applications in pain management. Sivopixant can be utilized in studies investigating the role of purinergic signaling in nociception and related disorders.
Chemical Information
| Catalog Num | A67894 |
|---|---|
| M. Wt | 507.93 |
| Formula | C25H22ClN5O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2414285-40-6 |
| Synonyms | S-600918 |
| SMILES | O=C(N(C1=O)C[C@H](C)C(O)=O)N/C(N1CC2=CC=C(C=C2)Cl)=N\C3=CC=C(C=C3)OC4=CC=CC=N4 |
Biological Activity
| Description | Sivopixant is a selective antagonist of the P2X3 receptor, exhibiting a potent inhibitory activity with an IC50 of 4.2 nM for P2X3 and 1100 nM for P2X2/3. This compound demonstrates significant analgesic properties, making it valuable for research focused on pain pathways and therapeutic applications in pain management. Sivopixant can be utilized in studies investigating the role of purinergic signaling in nociception and related disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
