Product Data Sheet
Ro 0437626
Catalog No. A67909
Ro 0437626 is a selective antagonist of the purinergic P2X1 receptor, exhibiting an IC50 value of 3 μM. It demonstrates low affinity for P2X2, P2X3, and P2X2/3 receptors, with IC50 values exceeding 100 μM. This compound is valuable for research applications involving the modulation of P2X1 receptor signaling pathways, contributing to studies in cardiovascular and pain research.
Chemical Information
| Catalog Num | A67909 |
|---|---|
| M. Wt | 525.66 |
| Formula | C27H35N5O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 134362-79-1 |
| Synonyms | |
| SMILES | O=C(C1=NC2=CC=CC=C2N1)N[C@H](CC3=CSC=N3)C(N[C@@H](CC4CCCCC4)[C@@H](O)[C@H](C5CC5)O)=O |
Biological Activity
| Description | Ro 0437626 is a selective antagonist of the purinergic P2X1 receptor, exhibiting an IC50 value of 3 μM. It demonstrates low affinity for P2X2, P2X3, and P2X2/3 receptors, with IC50 values exceeding 100 μM. This compound is valuable for research applications involving the modulation of P2X1 receptor signaling pathways, contributing to studies in cardiovascular and pain research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
