Product Data Sheet

Iso-PPADS tetrasodium

Catalog No. A67919

main product photo
Iso-PPADS tetrasodium is a selective antagonist of the P2X purinoceptors, specifically targeting P2X1 and P2X3 receptors with IC50 values of 43 nM and 84 nM, respectively. This compound is known for its neuroprotective effects, particularly in the context of ventilator-induced brain injury (VIBI). Iso-PPADS tetrasodium is useful for researchers investigating purinergic signaling pathways and their implications in various neurological conditions.
Chemical Information
Catalog NumA67919
M. Wt599.30
FormulaC14H10N3Na4O12PS2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.207572-67-6
Synonyms
SMILESO=S(C1=CC=C(S(=O)(O[Na])=O)C=C1/N=N/C2=NC(C)=C(O)C(C=O)=C2COP(O[Na])(O[Na])=O)(O[Na])=O
Biological Activity
DescriptionIso-PPADS tetrasodium is a selective antagonist of the P2X purinoceptors, specifically targeting P2X1 and P2X3 receptors with IC50 values of 43 nM and 84 nM, respectively. This compound is known for its neuroprotective effects, particularly in the context of ventilator-induced brain injury (VIBI). Iso-PPADS tetrasodium is useful for researchers investigating purinergic signaling pathways and their implications in various neurological conditions.
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