P2X3 antagonist 37
Catalog No. A67924

P2X3 antagonist 37 is a selective antagonist of the P2X3 receptor, exhibiting an inhibitory concentration (IC50) of 32.45 nM for human P2X3. This compound interrupts ATP-mediated signaling, making it a valuable tool for research into pain pathways and bladder dysfunction. It supports investigations exploring P2X3 receptor roles in neurobiology and related therapeutic applications.
Chemical Information
| Catalog Num | A67924 |
|---|---|
| M. Wt | 431.30 |
| Formula | C18H9F4N7O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2649318-40-9 |
| Synonyms | |
| SMILES | O=C(NC1=NC=C(F)C=C1)CN2C3=CC(C#N)=NN3C4=NC(C(F)(F)F)=CC=C4C2=O |
Biological Activity
| Description | P2X3 antagonist 37 is a selective antagonist of the P2X3 receptor, exhibiting an inhibitory concentration (IC50) of 32.45 nM for human P2X3. This compound interrupts ATP-mediated signaling, making it a valuable tool for research into pain pathways and bladder dysfunction. It supports investigations exploring P2X3 receptor roles in neurobiology and related therapeutic applications. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


