Product Data Sheet
HW091077
Catalog No. A67936
HW091077 is a selective antagonist of the P2X3 receptor, exhibiting an IC50 of 17 nM. By inhibiting ATP-induced calcium influx and preventing cell depolarization, HW091077 effectively disrupts cough reflex pathways. This compound holds potential for research applications focused on chronic cough mechanisms.
Chemical Information
| Catalog Num | A67936 |
|---|---|
| M. Wt | 498.49 |
| Formula | C22H22F4N4O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2766757-56-4 |
| Synonyms | |
| SMILES | FC1=C(C2=NC=C(C)S2)C=C(C=C1C(N[C@@H](C3=CN=C(C(F)(F)F)N=C3)C)=O)O[C@@H](C)[C@@H](O)C |
Biological Activity
| Description | HW091077 is a selective antagonist of the P2X3 receptor, exhibiting an IC50 of 17 nM. By inhibiting ATP-induced calcium influx and preventing cell depolarization, HW091077 effectively disrupts cough reflex pathways. This compound holds potential for research applications focused on chronic cough mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
