Product Data Sheet

P2X7 receptor antagonist-6

Catalog No. A67937

main product photo
P2X7 receptor antagonist-6 is a negative allosteric modulator targeting the P2X7 receptor, exhibiting an IC50 of 1.31 μM for human P2X7. This compound demonstrates potential for research applications in cancer, neurodegenerative disorders, inflammatory responses, and infectious diseases, contributing to a greater understanding of P2X7's role in these conditions. Its specificity and efficacy make it a valuable tool for exploring therapeutic pathways in related research fields.
Chemical Information
Catalog NumA67937
M. Wt410.41
FormulaC23H20F2N2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1114621-31-6
Synonyms
SMILESO=C(NC(CC1=CC=C(C=C1)F)CC2=CC=C(C=C2)F)NC3=CC4=C(OCO4)C=C3
Biological Activity
DescriptionP2X7 receptor antagonist-6 is a negative allosteric modulator targeting the P2X7 receptor, exhibiting an IC50 of 1.31 μM for human P2X7. This compound demonstrates potential for research applications in cancer, neurodegenerative disorders, inflammatory responses, and infectious diseases, contributing to a greater understanding of P2X7's role in these conditions. Its specificity and efficacy make it a valuable tool for exploring therapeutic pathways in related research fields.
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