Product Data Sheet
Margatoxin
Catalog No. A67975
Margatoxin is a highly selective inhibitor of the voltage-gated potassium channel Kv1.3, with a binding affinity (Kd) of 11.7 pM. It also exhibits inhibitory effects on Kv1.2 (Kd = 6.4 pM) and Kv1.1 (Kd = 4.2 nM). This 39-amino-acid peptide, derived from the venom of Centruroides margaritatus, is extensively utilized in ion channel research to study the role of Kv1.3 in various physiological and pathophysiological processes.
Chemical Information
| Catalog Num | A67975 |
|---|---|
| M. Wt | 4178.95 |
| Formula | C178H286N52O50S7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 145808-47-5 |
| Synonyms | |
| SMILES |
Biological Activity
| Description | Margatoxin is a highly selective inhibitor of the voltage-gated potassium channel Kv1.3, with a binding affinity (Kd) of 11.7 pM. It also exhibits inhibitory effects on Kv1.2 (Kd = 6.4 pM) and Kv1.1 (Kd = 4.2 nM). This 39-amino-acid peptide, derived from the venom of Centruroides margaritatus, is extensively utilized in ion channel research to study the role of Kv1.3 in various physiological and pathophysiological processes. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
