Product Data Sheet
PNU 37883 hydrochloride
Catalog No. A68015
PNU 37883 hydrochloride is a selective blocker of ATP-sensitive potassium (KATP) channels, specifically targeting the Kir6 subunit. This compound exerts diuretic effects through its selective binding in renal tissue and vascular smooth muscle, while exhibiting minimal interaction with brain or pancreatic beta cells. PNU 37883 hydrochloride is useful for research applications related to cardiovascular physiology and renal function studies.
Chemical Information
| Catalog Num | A68015 |
|---|---|
| M. Wt | 381.98 |
| Formula | C21H36ClN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 57568-80-6 |
| Synonyms | PNU 37883A |
| SMILES | [H]Cl.N1(/C(NC2CCCCC2)=N\C3(C4)CC5CC4CC(C5)C3)CCOCC1 |
Biological Activity
| Description | PNU 37883 hydrochloride is a selective blocker of ATP-sensitive potassium (KATP) channels, specifically targeting the Kir6 subunit. This compound exerts diuretic effects through its selective binding in renal tissue and vascular smooth muscle, while exhibiting minimal interaction with brain or pancreatic beta cells. PNU 37883 hydrochloride is useful for research applications related to cardiovascular physiology and renal function studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
