Product Data Sheet

A2793

Catalog No. A68026

main product photo
A2793 is a selective inhibitor of the TWIK-related acid-sensitive K+ channels, TASK-1 and TRESK. With an IC50 of 6.8 μM for mTRESK, this reagent demonstrates significant activity against TRESK while exhibiting only moderate effects on TREK-1 and TALK-1. A2793 is valuable for research applications focusing on ion channel regulation and neurological studies.
Chemical Information
Catalog NumA68026
M. Wt265.69
FormulaC13H12ClNO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.88349-90-0
Synonyms
SMILESO=C(OCC)COC1=C2N=CC=CC2=C(Cl)C=C1
Biological Activity
DescriptionA2793 is a selective inhibitor of the TWIK-related acid-sensitive K+ channels, TASK-1 and TRESK. With an IC50 of 6.8 μM for mTRESK, this reagent demonstrates significant activity against TRESK while exhibiting only moderate effects on TREK-1 and TALK-1. A2793 is valuable for research applications focusing on ion channel regulation and neurological studies.
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