Product Data Sheet

IDOR-1104-0086

Catalog No. A68038

main product photo
IDOR-1104-0086 is an orally active Kv7 channel opener, demonstrating an EC50 of 210 nM and the ability to cross the blood-brain barrier. This compound exhibits strong selectivity against the hERG channel, with an IC20 of 25 μM. IDOR-1104-0086 has shown efficacy in rodent models of epilepsy and possesses a favorable tolerability profile, making it a valuable tool for research in epilepsy and related neurological disorders.
Chemical Information
Catalog NumA68038
M. Wt334.28
FormulaC15H15F5N2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2756581-81-2
Synonyms
SMILESO=C(NCC1=CC=CC(C(F)(F)F)=C1)NC2(C3)CC3(C(F)F)C2
Biological Activity
DescriptionIDOR-1104-0086 is an orally active Kv7 channel opener, demonstrating an EC50 of 210 nM and the ability to cross the blood-brain barrier. This compound exhibits strong selectivity against the hERG channel, with an IC20 of 25 μM. IDOR-1104-0086 has shown efficacy in rodent models of epilepsy and possesses a favorable tolerability profile, making it a valuable tool for research in epilepsy and related neurological disorders.
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