Product Data Sheet
SKA-111
Catalog No. A68043
SKA-111 is a selective activator of the potassium channel KCa 3.1, promoting membrane hyperpolarization in porcine endothelial cells. This compound enhances Bradykinin induced coronary dilations in isolated rat heart models. SKA-111 is valuable for cardiovascular disease research, particularly in studies exploring potassium channel modulation and endothelial function.
| Catalog Num | A68043 |
|---|---|
| M. Wt | 214.29 |
| Formula | C12H10N2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1369170-24-0 |
| Synonyms | |
| SMILES | NC1=NC2=C3C=CC=CC3=C(C)C=C2S1 |
| Description | SKA-111 is a selective activator of the potassium channel KCa 3.1, promoting membrane hyperpolarization in porcine endothelial cells. This compound enhances Bradykinin induced coronary dilations in isolated rat heart models. SKA-111 is valuable for cardiovascular disease research, particularly in studies exploring potassium channel modulation and endothelial function. |
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