Product Data Sheet
Glipizide-d11
Catalog No. A68044
Glipizide-d11 is a deuterium-labeled derivative of Glipizide, a sulfonylurea-class anti-diabetic agent. It demonstrates potent activity in the management of type 2 diabetes mellitus by partially inhibiting ATP-sensitive potassium (KATP) channels in the β cells of the pancreatic islets of Langerhans. This stable isotope form is utilized in pharmacokinetic studies and metabolic research, helping to better elucidate the drug's pharmacodynamics and biological interactions.
Chemical Information
| Catalog Num | A68044 |
|---|---|
| M. Wt | 456.60 |
| Formula | C21H16D11N5O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1189426-07-0 |
| Synonyms | |
| SMILES | [2H]C1([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])NC(NS(=O)(C2=CC=C(C=C2)CCNC(C3=NC=C(C)N=C3)=O)=O)=O |
Biological Activity
| Description | Glipizide-d11 is a deuterium-labeled derivative of Glipizide, a sulfonylurea-class anti-diabetic agent. It demonstrates potent activity in the management of type 2 diabetes mellitus by partially inhibiting ATP-sensitive potassium (KATP) channels in the β cells of the pancreatic islets of Langerhans. This stable isotope form is utilized in pharmacokinetic studies and metabolic research, helping to better elucidate the drug's pharmacodynamics and biological interactions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
