Product Data Sheet
AZSMO-23
Catalog No. A68055
AZSMO-23 is a potent activator of the hERG K+ channel, demonstrating effective modulation of wild-type hERG pre-pulse and tail currents with EC50 values of 28.6 µM and 11.2 µM, respectively. This compound is particularly relevant for studies investigating long QT syndrome, offering insights into cardiac repolarization and related disorders. Researchers can utilize AZSMO-23 to explore the therapeutic potential and underlying mechanisms of hERG channel dysfunction.
Chemical Information
| Catalog Num | A68055 |
|---|---|
| M. Wt | 348.79 |
| Formula | C19H13ClN4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 496793-75-0 |
| Synonyms | |
| SMILES | O=C(C1=CC=CN=C1)NC2=CC=C(Cl)C(C3=NC4=CC=CC=C4N3)=C2 |
Biological Activity
| Description | AZSMO-23 is a potent activator of the hERG K+ channel, demonstrating effective modulation of wild-type hERG pre-pulse and tail currents with EC50 values of 28.6 µM and 11.2 µM, respectively. This compound is particularly relevant for studies investigating long QT syndrome, offering insights into cardiac repolarization and related disorders. Researchers can utilize AZSMO-23 to explore the therapeutic potential and underlying mechanisms of hERG channel dysfunction. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
