Product Data Sheet

UK-66914

Catalog No. A68117

main product photo
UK-66914 is a selective potassium channel inhibitor that targets the delayed rectifier potassium current (I_K). This compound is designed to prolong action potential duration (APD) and enhance the cardiac refractory period, which may aid in terminating reentry mechanisms in arrhythmias. Its mechanism of action allows for therapeutic effects without the adverse side effects typically associated with antiarrhythmic agents that modulate sodium and calcium currents, making it valuable for cardiac research applications.
Chemical Information
Catalog NumA68117
M. Wt376.47
FormulaC18H24N4O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.113049-11-9
Synonyms
SMILESCS(=O)(NC1=CC=C(C=C1)C(CN2CCN(CC2)C3=CC=NC=C3)O)=O
Biological Activity
DescriptionUK-66914 is a selective potassium channel inhibitor that targets the delayed rectifier potassium current (I_K). This compound is designed to prolong action potential duration (APD) and enhance the cardiac refractory period, which may aid in terminating reentry mechanisms in arrhythmias. Its mechanism of action allows for therapeutic effects without the adverse side effects typically associated with antiarrhythmic agents that modulate sodium and calcium currents, making it valuable for cardiac research applications.
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