Product Data Sheet
OSK-1
Catalog No. A68130
OSK-1 is a potent blocker of voltage-gated potassium (Kv) channels, specifically exhibiting IC50 values of 0.6 nM, 5.4 nM, and 0.014 nM for Kv1.1, Kv1.2, and Kv1.3, respectively. Additionally, OSK-1 demonstrates moderate activity against the Ca2+-activated KCa3.1 channel, with an IC50 of 225 nM. As a member of the α-KTx3 toxin family, OSK-1 serves as an immunosuppressive agent and is valuable in research exploring potassium channel modulation and its effects on cellular signaling pathways.
Chemical Information
| Catalog Num | A68130 |
|---|---|
| M. Wt | 4205.17 |
| Formula | C177H300N56O46S8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 183815-75-0 |
| Synonyms | |
| SMILES |
Biological Activity
| Description | OSK-1 is a potent blocker of voltage-gated potassium (Kv) channels, specifically exhibiting IC50 values of 0.6 nM, 5.4 nM, and 0.014 nM for Kv1.1, Kv1.2, and Kv1.3, respectively. Additionally, OSK-1 demonstrates moderate activity against the Ca2+-activated KCa3.1 channel, with an IC50 of 225 nM. As a member of the α-KTx3 toxin family, OSK-1 serves as an immunosuppressive agent and is valuable in research exploring potassium channel modulation and its effects on cellular signaling pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
