Product Data Sheet
UK-78282
Catalog No. A68141
UK-78282 is a selective inhibitor of the Kv1.3 voltage-gated potassium channel, exhibiting an IC50 of 200 nM. In addition to its primary target, UK-78282 also inhibits the Kv1.4 potassium channel. This compound demonstrates significant effects on human T cell activation, making it a valuable tool for studying immune responses and potential therapeutic applications in autoimmune diseases.
Chemical Information
| Catalog Num | A68141 |
|---|---|
| M. Wt | 429.59 |
| Formula | C29H35NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 191217-42-2 |
| Synonyms | |
| SMILES | COC1=CC=C(CCCN2CCC(COC(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C=C1 |
Biological Activity
| Description | UK-78282 is a selective inhibitor of the Kv1.3 voltage-gated potassium channel, exhibiting an IC50 of 200 nM. In addition to its primary target, UK-78282 also inhibits the Kv1.4 potassium channel. This compound demonstrates significant effects on human T cell activation, making it a valuable tool for studying immune responses and potential therapeutic applications in autoimmune diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
