Product Data Sheet

JTV-506

Catalog No. A68150

main product photo
JTV-506 is a potent ATP-sensitive potassium channel opener that primarily targets KATP channels. It effectively inhibits histamine-induced contractions in tracheal smooth muscle and reduces pulmonary vascular tone through direct action on vascular smooth muscle cells. JTV-506 serves as a valuable tool in pulmonary hypertension research, facilitating investigations into therapeutic strategies for managing this condition.
Chemical Information
Catalog NumA68150
M. Wt386.40
FormulaC19H22N4O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.170148-29-5
Synonyms
SMILESN#CC1=CC=C2C([C@@H](NC(C=C3)=NN(C)C3=O)[C@H](O)C(COC)(COC)O2)=C1
Biological Activity
DescriptionJTV-506 is a potent ATP-sensitive potassium channel opener that primarily targets KATP channels. It effectively inhibits histamine-induced contractions in tracheal smooth muscle and reduces pulmonary vascular tone through direct action on vascular smooth muscle cells. JTV-506 serves as a valuable tool in pulmonary hypertension research, facilitating investigations into therapeutic strategies for managing this condition.
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SHIPPING AND STORAGE
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