Product Data Sheet
Rilmakalim
Catalog No. A68151
Rilmakalim is a potassium channel opener that primarily targets ATP-sensitive K+ channels. It enhances potassium efflux, leading to hyperpolarization of the cell membrane, which can result in vasodilation and decreased heart muscle contractility. Rilmakalim is widely utilized in research investigating cardiovascular physiology, diabetic complications, and neuroprotection, particularly in the context of cardiac and vascular health.
Chemical Information
| Catalog Num | A68151 |
|---|---|
| M. Wt | 401.48 |
| Formula | C21H23NO5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 132014-21-2 |
| Synonyms | HOE 234 |
| SMILES | O=C1N(CCC1)[C@H]2[C@@H](C(C)(OC3=C2C=C(C=C3)S(=O)(C4=CC=CC=C4)=O)C)O |
Biological Activity
| Description | Rilmakalim is a potassium channel opener that primarily targets ATP-sensitive K+ channels. It enhances potassium efflux, leading to hyperpolarization of the cell membrane, which can result in vasodilation and decreased heart muscle contractility. Rilmakalim is widely utilized in research investigating cardiovascular physiology, diabetic complications, and neuroprotection, particularly in the context of cardiac and vascular health. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
