Product Data Sheet
AVE-0118
Catalog No. A68154
AVE-0118 is a nonselective blocker of the voltage-gated potassium channel Kv1.5, exhibiting an IC50 of 1.1 μM. This compound functions as a multichannel inhibitor with micromolar activity against Kv1.5 and several other ion channels, while demonstrating inactivity towards IKs, IKATP, and L-type calcium channels. AVE-0118 is useful in research related to cardiac action potentials and can aid in the study of ion channel pharmacology.
Chemical Information
| Catalog Num | A68154 |
|---|---|
| M. Wt | 479.57 |
| Formula | C30H29N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 498577-53-0 |
| Synonyms | |
| SMILES | O=C(NCCC1=CC=CN=C1)C2=CC=CC=C2C3=CC=CC=C3CNC(CC4=CC=C(C=C4)OC)=O |
Biological Activity
| Description | AVE-0118 is a nonselective blocker of the voltage-gated potassium channel Kv1.5, exhibiting an IC50 of 1.1 μM. This compound functions as a multichannel inhibitor with micromolar activity against Kv1.5 and several other ion channels, while demonstrating inactivity towards IKs, IKATP, and L-type calcium channels. AVE-0118 is useful in research related to cardiac action potentials and can aid in the study of ion channel pharmacology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
