Product Data Sheet

KCNT1-IN-3

Catalog No. A68164

main product photo
KCNT1-IN-3 is a selective inhibitor of the potassium channel KCNT1, exhibiting an IC50 of 30 nM against wild-type human KCNT1. This compound is valuable for investigating the role of KCNT1 in epilepsy and related neurological conditions. Its potency allows for detailed studies into the modulation of ion channel activity and its implications in neuronal excitability.
Chemical Information
Catalog NumA68164
M. Wt396.32
FormulaC16H15F3N6O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2540501-85-5
Synonyms
SMILESCOC1=NC=CC(C2=NOC([C@@H](NC(C3=CC(C(F)(F)F)=NN3C)=O)C)=N2)=C1
Biological Activity
DescriptionKCNT1-IN-3 is a selective inhibitor of the potassium channel KCNT1, exhibiting an IC50 of 30 nM against wild-type human KCNT1. This compound is valuable for investigating the role of KCNT1 in epilepsy and related neurological conditions. Its potency allows for detailed studies into the modulation of ion channel activity and its implications in neuronal excitability.
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