Product Data Sheet
Tedisamil
Catalog No. A68170
Tedisamil is an antiarrhythmic agent primarily targeting the transient outward potassium current (I(to)) in the atrium, leading to a significant reduction in heart rate. This compound also inhibits various potassium currents, including IK and K(ATP), as well as PKA-activated chloride channels, ultimately prolonging the cardiac action potential and QT interval. Tedisamil demonstrates effective antiarrhythmic properties against ventricular arrhythmias and atrial flutter in preclinical animal models, making it a valuable tool for cardiovascular research.
Chemical Information
| Catalog Num | A68170 |
|---|---|
| M. Wt | 288.47 |
| Formula | C19H32N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 90961-53-8 |
| Synonyms | KC-8857 |
| SMILES | [C@@H](CN1CC2CC2)(C3)C4(CCCC4)[C@@H](C1)CN3CC5CC5 |
Biological Activity
| Description | Tedisamil is an antiarrhythmic agent primarily targeting the transient outward potassium current (I(to)) in the atrium, leading to a significant reduction in heart rate. This compound also inhibits various potassium currents, including IK and K(ATP), as well as PKA-activated chloride channels, ultimately prolonging the cardiac action potential and QT interval. Tedisamil demonstrates effective antiarrhythmic properties against ventricular arrhythmias and atrial flutter in preclinical animal models, making it a valuable tool for cardiovascular research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
