Product Data Sheet

Dendrotoxin K

Catalog No. A68182

main product photo
Dendrotoxin K is a selective blocker of the Kv1.1 potassium channel, influencing neuronal excitability. It modulates glutamate release in CA3 neurons in a time-dependent manner by altering the presynaptic spike waveform, making it a valuable tool for studying synaptic transmission and neuronal signaling. This compound is useful for investigations into neuronal circuit dynamics and pathophysiological conditions involving ion channel function.
Chemical Information
Catalog NumA68182
M. Wt6559.66
FormulaC294H462N84O75S6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.119128-61-9
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SMILES
Biological Activity
DescriptionDendrotoxin K is a selective blocker of the Kv1.1 potassium channel, influencing neuronal excitability. It modulates glutamate release in CA3 neurons in a time-dependent manner by altering the presynaptic spike waveform, making it a valuable tool for studying synaptic transmission and neuronal signaling. This compound is useful for investigations into neuronal circuit dynamics and pathophysiological conditions involving ion channel function.
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