Product Data Sheet

Dofetilide N-oxide

Catalog No. A68192

main product photo
Dofetilide N-oxide is a metabolite of the class III antiarrhythmic agent Dofetilide, primarily targeting potassium channels. Its mechanism involves the inhibition of potassium ion movement, which plays a crucial role in the regulation of cardiac action potentials. This compound is utilized in research to study cardiac arrhythmias and the therapeutic potential of potassium channel blockers in managing cardiovascular diseases.
Chemical Information
Catalog NumA68192
M. Wt457.56
FormulaC19H27N3O6S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.144449-71-8
SynonymsUK-116856
SMILESCS(=O)(NC1=CC=C(CC[N+](CCOC2=CC=C(NS(=O)(C)=O)C=C2)(C)[O-])C=C1)=O
Biological Activity
DescriptionDofetilide N-oxide is a metabolite of the class III antiarrhythmic agent Dofetilide, primarily targeting potassium channels. Its mechanism involves the inhibition of potassium ion movement, which plays a crucial role in the regulation of cardiac action potentials. This compound is utilized in research to study cardiac arrhythmias and the therapeutic potential of potassium channel blockers in managing cardiovascular diseases.
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