Product Data Sheet

VU0405601

Catalog No. A68229

main product photo
VU0405601 is a potent activator of the KV11.1 ion channel, which plays a crucial role in cardiac repolarization. This compound has demonstrated the ability to protect cardiac tissue from dofetilide-induced ventricular tachycardia, making it valuable for research into arrhythmias and cardiac safety. Its mechanism of action positions it as a significant tool for studying cardiac electrophysiology and developing therapeutic strategies for related heart conditions.
Chemical Information
Catalog NumA68229
M. Wt357.20
FormulaC17H13BrN2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.712325-30-9
Synonyms
SMILESO=C(COC1=CC=C2C=CC=CC2=C1Br)NC3=CC=CN=C3
Biological Activity
DescriptionVU0405601 is a potent activator of the KV11.1 ion channel, which plays a crucial role in cardiac repolarization. This compound has demonstrated the ability to protect cardiac tissue from dofetilide-induced ventricular tachycardia, making it valuable for research into arrhythmias and cardiac safety. Its mechanism of action positions it as a significant tool for studying cardiac electrophysiology and developing therapeutic strategies for related heart conditions.
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