Product Data Sheet
KCa2 channel modulator 2
Catalog No. A68234
KCa2 Channel Modulator 2 is a potent positive modulator of the KCa2 channel subtypes, specifically targeting KCa2.2a and KCa2.3. This compound demonstrates comparable efficacy with EC50 values of 0.64 μM for rat KCa2.2a and 0.60 μM for human KCa2.3 channels. Its selective modulation makes it suitable for investigations into the physiological roles of KCa2 channels and their potential implications in therapeutic applications related to calcium signaling and excitability in various tissues.
Chemical Information
| Catalog Num | A68234 |
|---|---|
| M. Wt | 331.78 |
| Formula | C16H15ClFN5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2764618-34-8 |
| Synonyms | |
| SMILES | CC1=CC(NC2=C(C=CC(Cl)=C2)F)=NC(N3C(C)=CC(C)=N3)=N1 |
Biological Activity
| Description | KCa2 Channel Modulator 2 is a potent positive modulator of the KCa2 channel subtypes, specifically targeting KCa2.2a and KCa2.3. This compound demonstrates comparable efficacy with EC50 values of 0.64 μM for rat KCa2.2a and 0.60 μM for human KCa2.3 channels. Its selective modulation makes it suitable for investigations into the physiological roles of KCa2 channels and their potential implications in therapeutic applications related to calcium signaling and excitability in various tissues. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
