Product Data Sheet

L-702958

Catalog No. A68239

main product photo
L-702958 is a potent blocker of the human ether-à-go-go-related gene (hERG) potassium channel with an IC50 of 14.3 nM. This compound exhibits significant antiarrhythmic activity, making it valuable for research into the mechanisms underlying arrhythmias and potential therapeutic applications. L-702958 is essential for studies focused on cardiac electrophysiology and ion channel modulation.
Chemical Information
Catalog NumA68239
M. Wt465.56
FormulaC25H27N3O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.136081-07-7
Synonyms
SMILESO=C1CC2(CCN([C@H]3CC4=CC=C(C#N)C=C4CC3)CC2)OC5=C1C=C(NS(C)(=O)=O)C=C5
Biological Activity
DescriptionL-702958 is a potent blocker of the human ether-à-go-go-related gene (hERG) potassium channel with an IC50 of 14.3 nM. This compound exhibits significant antiarrhythmic activity, making it valuable for research into the mechanisms underlying arrhythmias and potential therapeutic applications. L-702958 is essential for studies focused on cardiac electrophysiology and ion channel modulation.
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