Product Data Sheet

VU714 oxalate

Catalog No. A68254

main product photo
VU714 oxalate is a selective inhibitor of the Kir7.1 potassium channel, impacting channel activity by enhancing the blockade induced by other structurally distinct inhibitors. This compound modulates the pharmacological profile of Kir channels through interactions with critical amino acid residues, making it a valuable tool for investigating Kir channel functions. It is applicable in research focused on cardiovascular, renal, and neurological areas where potassium channels play crucial roles.
Chemical Information
Catalog NumA68254
M. Wt456.92
FormulaC24H25ClN2O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.474625-52-0
Synonyms
SMILESOC1=C2N=CC=CC2=C(Cl)C=C1CN3CCC(CC4=CC=CC=C4)CC3.O=C(O)C(O)=O
Biological Activity
DescriptionVU714 oxalate is a selective inhibitor of the Kir7.1 potassium channel, impacting channel activity by enhancing the blockade induced by other structurally distinct inhibitors. This compound modulates the pharmacological profile of Kir channels through interactions with critical amino acid residues, making it a valuable tool for investigating Kir channel functions. It is applicable in research focused on cardiovascular, renal, and neurological areas where potassium channels play crucial roles.
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