Product Data Sheet

E-4031 free base

Catalog No. A68270

main product photo
E-4031 free base is a selective blocker of the hERG potassium channels, primarily involved in cardiac action potential repolarization. This compound is essential for studying the mechanisms of class III anti-arrhythmic agents and their effects on cardiac rhythm and arrhythmia. Its specificity for hERG channels makes it a valuable tool for investigating the pharmacological profiles of various therapeutic candidates in cardiological research.
Chemical Information
Catalog NumA68270
M. Wt401.52
FormulaC21H27N3O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.113558-89-7
Synonyms
SMILESCS(=O)(NC1=CC=C(C(C2CCN(CCC3=NC(C)=CC=C3)CC2)=O)C=C1)=O
Biological Activity
DescriptionE-4031 free base is a selective blocker of the hERG potassium channels, primarily involved in cardiac action potential repolarization. This compound is essential for studying the mechanisms of class III anti-arrhythmic agents and their effects on cardiac rhythm and arrhythmia. Its specificity for hERG channels makes it a valuable tool for investigating the pharmacological profiles of various therapeutic candidates in cardiological research.
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