Product Data Sheet
Tedisamil dihydrochloride
Catalog No. A68276
Tedisamil dihydrochloride is an antiarrhythmic agent primarily targeting the transient outward potassium current (I(to)) in cardiac tissue. This compound significantly slows heart rate by inhibiting multiple potassium channels, including IK, K(ATP), and PKA-activated chloride channels, which prolongs the cardiac action potential and QT interval. Tedisamil dihydrochloride is effective in demonstrating antiarrhythmic effects against ventricular arrhythmias and atrial flutter in various animal models, making it a valuable tool for cardiovascular research.
Chemical Information
| Catalog Num | A68276 |
|---|---|
| M. Wt | 361.39 |
| Formula | C19H34Cl2N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 132523-84-3 |
| Synonyms | KC-8857 dihydrochloride |
| SMILES | [C@@H](CN1CC2CC2)(C3)C4(CCCC4)[C@@H](C1)CN3CC5CC5.Cl.Cl |
Biological Activity
| Description | Tedisamil dihydrochloride is an antiarrhythmic agent primarily targeting the transient outward potassium current (I(to)) in cardiac tissue. This compound significantly slows heart rate by inhibiting multiple potassium channels, including IK, K(ATP), and PKA-activated chloride channels, which prolongs the cardiac action potential and QT interval. Tedisamil dihydrochloride is effective in demonstrating antiarrhythmic effects against ventricular arrhythmias and atrial flutter in various animal models, making it a valuable tool for cardiovascular research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
