Product Data Sheet
UCL-1848 TFA
Catalog No. A68296
UCL-1848 TFA is a potent blocker of the human small conductance calcium-activated potassium channel (hSK1), exhibiting an IC50 value of 1.1 nM. This compound is valuable for studies focused on the modulation of hSK1 activity and its role in cellular signaling pathways. Research applications include investigations into excitability in neurons and cardiac tissues, as well as potential therapeutic implications in various neurological and cardiovascular disorders.
Chemical Information
| Catalog Num | A68296 |
|---|---|
| M. Wt | 652.63 |
| Formula | C32H34F6N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 201147-53-7 |
| Synonyms | |
| SMILES | O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F.C1(NCCCCCNC2=C3C=CC=CC3=[N+]4C=C2)=CC=[N+](CCCCC4)C5=CC=CC=C15 |
Biological Activity
| Description | UCL-1848 TFA is a potent blocker of the human small conductance calcium-activated potassium channel (hSK1), exhibiting an IC50 value of 1.1 nM. This compound is valuable for studies focused on the modulation of hSK1 activity and its role in cellular signaling pathways. Research applications include investigations into excitability in neurons and cardiac tissues, as well as potential therapeutic implications in various neurological and cardiovascular disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
