Product Data Sheet
Lombazole
Catalog No. A68299
Lombazole is an antimicrobial agent that primarily targets potassium channels and inhibits lipid synthesis in bacterial membranes. It exhibits selective antibacterial activity by disrupting the de novo synthesis of cell enclosure in Staphylococcus aureus without significantly affecting potassium permeability. Additionally, Lombazole interferes with the sterol C-14 demethylation process in Candida albicans, highlighting its potential applications in studying membrane dynamics and lipid biosynthesis in infectious pathogens. This compound is valuable for researchers investigating membrane integrity and antimicrobial resistance mechanisms.
Chemical Information
| Catalog Num | A68299 |
|---|---|
| M. Wt | 344.84 |
| Formula | C22H17ClN2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 60628-98-0 |
| Synonyms | |
| SMILES | ClC1=C(C(N2C=NC=C2)C3=CC=C(C4=CC=CC=C4)C=C3)C=CC=C1 |
Biological Activity
| Description | Lombazole is an antimicrobial agent that primarily targets potassium channels and inhibits lipid synthesis in bacterial membranes. It exhibits selective antibacterial activity by disrupting the de novo synthesis of cell enclosure in Staphylococcus aureus without significantly affecting potassium permeability. Additionally, Lombazole interferes with the sterol C-14 demethylation process in Candida albicans, highlighting its potential applications in studying membrane dynamics and lipid biosynthesis in infectious pathogens. This compound is valuable for researchers investigating membrane integrity and antimicrobial resistance mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
