Product Data Sheet

ztz240

Catalog No. A68301

main product photo
ztz240 is a chemical modulator targeting the voltage-gated potassium channel Kv7 (KCNQ), specifically KCNQ2 and KCNQ3 with an EC50 of 6.1 μM, and KCNQ4 with an EC50 of 12.2 μM. This compound exhibits significant biological activity relevant to analgesia and anti-epileptic research. Its modulation of KCNQ channels makes it a valuable tool for studying the underlying mechanisms of pain and seizure disorders.
Chemical Information
Catalog NumA68301
M. Wt250.66
FormulaC12H8ClFN2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.325457-98-5
Synonyms
SMILESO=C(C1=CC=C(C=C1)F)NC2=CN=C(C=C2)Cl
Biological Activity
Descriptionztz240 is a chemical modulator targeting the voltage-gated potassium channel Kv7 (KCNQ), specifically KCNQ2 and KCNQ3 with an EC50 of 6.1 μM, and KCNQ4 with an EC50 of 12.2 μM. This compound exhibits significant biological activity relevant to analgesia and anti-epileptic research. Its modulation of KCNQ channels makes it a valuable tool for studying the underlying mechanisms of pain and seizure disorders.
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