Product Data Sheet
Nifekalant
Catalog No. A68319
Nifekalant is a class III antiarrhythmic agent that functions as a blocker of IKr potassium channels, exhibiting an IC50 value of 10 μM. This compound is primarily utilized in research focused on refractory ventricular tachyarrhythmias, providing valuable insights into cardiac rhythm management. Its ability to modulate potassium channel activity makes it an essential tool for studying arrhythmic conditions and potential therapeutic interventions.
Chemical Information
| Catalog Num | A68319 |
|---|---|
| M. Wt | 405.45 |
| Formula | C19H27N5O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 130636-43-0 |
| Synonyms | MS-551 free base |
| SMILES | O=C1N(C)C(C=C(NCCN(CCO)CCCC2=CC=C([N+]([O-])=O)C=C2)N1C)=O |
Biological Activity
| Description | Nifekalant is a class III antiarrhythmic agent that functions as a blocker of IKr potassium channels, exhibiting an IC50 value of 10 μM. This compound is primarily utilized in research focused on refractory ventricular tachyarrhythmias, providing valuable insights into cardiac rhythm management. Its ability to modulate potassium channel activity makes it an essential tool for studying arrhythmic conditions and potential therapeutic interventions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
