Product Data Sheet
Verucopeptin
Catalog No. A68332
Verucopeptin is a selective v-ATPase inhibitor that targets the ATP6V1G subunit, effectively reducing v-ATPase activity. This compound has a notable impact on HIF-1 signaling, decreasing the expression of HIF-1α and its target genes. Additionally, Verucopeptin demonstrates antitumor properties against multidrug resistant (MDR) cancers, making it a valuable tool for cancer research. Its specific mechanism and biological activity position it as a significant reagent for studies focused on tumor biology and therapy resistance.
Chemical Information
| Catalog Num | A68332 |
|---|---|
| M. Wt | 896.08 |
| Formula | C43H73N7O13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 138067-14-8 |
| Synonyms | |
| SMILES | N(C([C@@](C)(O)C1(O)O[C@H](\C(=C\[C@H](C[C@H](C[C@@H](CC)C)C)C)\C)[C@@H](OC)CC1)=O)[C@H]2[C@H](C(C)C)OC(=O)CN(C)C(=O)CNC(=O)CN(C)C(=O)CN(O)C(=O)[C@@]3(N(C2=O)NCCC3)[H] |
Biological Activity
| Description | Verucopeptin is a selective v-ATPase inhibitor that targets the ATP6V1G subunit, effectively reducing v-ATPase activity. This compound has a notable impact on HIF-1 signaling, decreasing the expression of HIF-1α and its target genes. Additionally, Verucopeptin demonstrates antitumor properties against multidrug resistant (MDR) cancers, making it a valuable tool for cancer research. Its specific mechanism and biological activity position it as a significant reagent for studies focused on tumor biology and therapy resistance. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
