Product Data Sheet

Linaprazan mesylate

Catalog No. A68354

main product photo
Linaprazan mesylate is a proton pump inhibitor that targets the H+,K+ -ATPase enzyme in the gastric mucosa through competitive binding with potassium ions. With an IC50 value of 1.0 ± 0.2 μM, it exhibits potent inhibitory effects on gastric acid secretion. This compound is particularly applicable in studies related to gastroesophageal reflux disease and reflux esophagitis, facilitating research on its therapeutic potential.
Chemical Information
Catalog NumA68354
M. Wt462.56
FormulaC22H30N4O5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.855998-67-3
SynonymsAZD-0865 mesylate
SMILESO=C(C1=CN2C(C(NCC3=C(C)C=CC=C3C)=C1)=NC(C)=C2C)NCCO.CS(=O)(O)=O
Biological Activity
DescriptionLinaprazan mesylate is a proton pump inhibitor that targets the H+,K+ -ATPase enzyme in the gastric mucosa through competitive binding with potassium ions. With an IC50 value of 1.0 ± 0.2 μM, it exhibits potent inhibitory effects on gastric acid secretion. This compound is particularly applicable in studies related to gastroesophageal reflux disease and reflux esophagitis, facilitating research on its therapeutic potential.
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